Project Details
Dynamic assembly, localization and rotation of the archaellum (A01)
Subject Area
Biochemistry
Term
since 2019
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 403222702
The archaellum is the motility machinery that archaea use to move in liquid media. It is evolutionary linked to bacterial type IV pili, but generates movement by a rotating filament which is driven by ATP hydrolysis. Using biochemical and structural methods, we aim to understand the modular assembly of the archaellum subunits and how their interplay enables torque generation. We will employ the model H. volcanii to gain spatio-temporal information of the assembly process in vivo.
DFG Programme
Collaborative Research Centres
Subproject of
SFB 1381:
Dynamic organization of cellular protein machineries: From biogenesis and modular assembly to function
Applicant Institution
Albert-Ludwigs-Universität Freiburg
Project Head
Professorin Dr. Sonja Verena Albers