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Organtoxizität durch Nukleosidanaloga in der HIV-Therapie im Mausmodell - Therapeutische Beeinflussbarkeit durch Uridin

Subject Area Rheumatology
Term from 2007 to 2010
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 42492194
 
Final Report Year 2012

Final Report Abstract

No abstract available

Publications

  • Uridine supplementation antagonizes zidovudine-induced mitochondrial myopathy and hyperlactatemia. Arthritis Rheum. (2008) 58:318-326
    D. Lebrecht, C. Deveaud, B. Beauvoit, J. Bonnet, J. Kirschner and UA. Walker
  • Gene transcription profiles and immunohistochemistry in adipose tissue of HIV-1 infected patients with NRTI-associated lipoatrophy. J Infect Dis. (2009) 200:252-262
    UA. Walker, M. Sievers, K. Sevastianova, B. Setzer, D. Wågsäter, P. Eriksson, H. Yki-Järvinen and J. Sutinen
  • Mitochondrial tubulopathy in tenofovir-DF treated rats. JAIDS (2009) 51:258-263
    D. Lebrecht, AC. Venhoff, J. Kirschner, T. Wiech, N. Venhoff and UA. Walker
  • MtDNA depletion in rat liver induced by fosalvudine tidoxil, a novel NRTI pro-drug. Antimicrobial Agents Chemother. (2009) 53:2748-51
    AC. Venhoff, D. Lebrecht, FU. Reuss, B. Heckl-Östreicher, R. Wehr, UA. Walker and N. Venhoff
  • Uridine supplementation with Mitocnol attenuates mitochondrial cardiomyopathy induced by zidovudine and zalcitabine. JAIDS. (2010)
    K. Balcarek, D. Lebrecht, C. Deveaud, B. Beauvoid, J. Bonnet, JB. Kirschner, N. Venhoff and UA. Walker
  • Uridine supplementation with Mitocnol attenuates the peripheral neuropathy and encephalopathy induced by antiretroviral nucleoside analogues. AIDS (2010) 24:345-52
    N. Venhoff, C. Deveaud, B. Beauvoit, J. Bonnet, AC. Venhoff, K. Müller, J. Kirschner, D. Lebrecht and UA. Walker
 
 

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