Printing of biofabricate and customized bioreactors for skeletal muscle tissue. (B03)

• Subject Area: Biomaterials ; Medical Physics, Biomedical Technology
• Term: since 2018
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 326998133

The aim of subproject B03 is the development of different composite bioinks with ion-releasing (bioreactive) particles and electrically conductive fillers for the bioprinting of skeletal muscle tissue.Basically, synergistic stimulation of cells and cell growth through electrical and biochemical factors for the formation of highly mature muscle tissue will be investigated in vitro. For this purpose, a bioreactor with complex structure and functionalities will be designed and fabricated using additive manufacturing, which will be tissue-specific and will enable the electromechanical stimulation of skeletal muscle tissue.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 225: From the fundamentals of biofabrication towards functional tissue models
• Applicant Institution: Julius-Maximilians-Universität Würzburg
• Project Heads: Professor Dr.-Ing. Aldo Boccaccini; Professor Dr.-Ing. Frank Döpper, since 1/2022; Professor Dr.-Ing. Jan Hansmann, until 12/2021; Privatdozentin Sahar Salehi-Müller, Ph.D.