Project Details
Disturbed B cell homeostasis of B cells in SLE: Delineation of intrinsic signaling abnormalities
Applicant
Professor Dr. Thomas Dörner
Subject Area
Rheumatology
Term
from 2017 to 2021
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 390780177
Final Report Year
2021
Final Report Abstract
No abstract available
Publications
- (2018). Anti-interleukin-6 signalling therapy rebalances the disrupted cytokine production of B cells from patients with active rheumatoid arthritis. Eur J Immunol 48, 194-203
Fleischer, S., Ries, S., Shen, P., Lheritier, A., Cazals, F., Burmester, G.R., Dorner, T., and Fillatreau, S.
(See online at https://doi.org/10.1002/eji.201747191) - (2019). Identification and Characterization of Post-activated B Cells in Systemic Autoimmune Diseases. Front Immunol 10, 2136
Weissenberg, S.Y., Szelinski, F., Schrezenmeier, E., Stefanski, A.L., Wiedemann, A., Rincon- Arevalo, H., Welle, A., Jungmann, A., Nordstrom, K., Walter, J., et al.
(See online at https://doi.org/10.3389/fimmu.2019.02136) - (2020). Therapeutic implications of the anergic/postactivated status of B cells in systemic lupus erythematosus. RMD Open 6
Dorner, T., Szelinski, F., Lino, A.C., and Lipsky, P.E.
(See online at https://doi.org/10.1136/rmdopen-2020-001258) - (2021). Toll-like receptor signalling in B cells during systemic lupus erythematosus.Nat Rev Rheumatol. 17:98-108
Fillatreau S, Manfroi B, Dörner T
(See online at https://doi.org/10.1038/s41584-020-00544-4)