Steroid hormones and cancer immunity – learning from adrenocortical carcinoma (B16)

• Subject Area: Endocrinology, Diabetology, Metabolism ; Hematology, Oncology
• Term: since 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 314061271

(I) Elucidate ACC-specific resistance mechanisms and biomarkers of response to immunotherapy.(II) Determine the effects of combined immune checkpoint inhibition and anti-glucocorticoid treatment in vitro and in vivo. (III) Identify novel treatment strategies for an improved immunotherapy against ACC.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 205: The Adrenal: Central Relay in Health and Disease
• Applicant Institution: Technische Universität Dresden
• Project Heads: Professor Dr. Martin Fassnacht; Professor Matthias Kroiß, Ph.D.