Retinal Disease Models as a Tool for Understanding Robust Vision (14)

• Subject Area: Cognitive, Systems and Behavioural Neurobiology ; Ophthalmology
• Term: since 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 276693517

The healthy human retina supports robust visual processing, leading to stable contrast and brightness perception over a broad range of conditions. Interestingly, once vision has properly developed, it remains remarkably robust even if certain retinal cells start to degen-erate due to retinal diseases. The objective of this project is to study the robustness and flexibility of visual task performance in human RP (retinitis pigmentosa) and CSNB1 (complete congenital stationary night blindness) patients and in corresponding animal disease models by linking visual performance to underlying cellular function.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1233: Robust Vision - Inference Principles and Neural Mechanisms
• Applicant Institution: Eberhard Karls Universität Tübingen
• Project Heads: Professor Dr. Jakob Macke, until 12/2020; Christina Schwarz, Ph.D.; Privatdozentin Dr. Katarina Stingl; Professor Dr. Günther Zeck; Professor Dr. Eberhart Zrenner, until 12/2020