Development and refinement of mouse models for studying stress resilience (Z02)

• Subject Area: Biological Psychiatry
• Term: from 2016 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 264810226

The overarching aim of this central project is to set the animal experimental basis of this CRC in order to promote the understanding of neurobiological mechanisms underlying resilience to stress-related mental dysfunctions. Z02 will continue to work on the improvement of resilience models and the definition of valid resilience-related outcomes and will follow a twofold strategy: First, Z02 provides state-of-the art service for mouse models to be used in other subprojects of this CRC. Second, Z02 will address a number of specific fundamental scientific questions about the validity and refinement of resilience models thereby advancing mechanistic insights but also contributing to the development of a better conceptual-theoretical framework.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1193: Neurobiology of Resilience to stress-related mental dysfunction: from understanding mechanisms to promoting prevention
• Applicant Institution: Johannes Gutenberg-Universität Mainz
• Project Heads: Professor Dr. Beat Lutz; Professorin Dr. Marianne Müller