Bifunctional hybrid nanoparticles via calcium carbonate crystallization driven by engineered protein surfaces (A07)

• Subject Area: Physical Chemistry of Molecules, Liquids and Interfaces, Biophysical Chemistry ; Biological and Biomimetic Chemistry
• Term: from 2016 to 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 268730352

This project aims at the defined generation of structurally and functionally anisotropic nanohybrid particles of calcium carbonate and tailor-made genetically engineered proteins via non-classical pathways of crystallization. Iterative cycles of protein design and thorough investigations of their effect on in vitro calcium carbonate precipitation will identify the essential factors underlying this complex process. Eventually, this will pave the way for the rational generation of particle superstructures via directed self-assembly.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1214: Anisotropic Particles as Building Blocks: Tailoring Shape, Interactions and Structures
• Applicant Institution: Universität Konstanz
• Project Heads: Professor Dr. Denis Gebauer; Professor Dr. Andreas Marx