Elucidation of the mechanisms determining neural stem cells fate and identification of the niche in the adult SVZ and hippocampus

Applicant Professor Dr. Verdon Taylor, Ph.D.

Subject Area Developmental Neurobiology

Term from 2006 to 2010

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 28996474

Final Report Year 2010

Final Report Abstract

No abstract available

(2009). Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh. Nat Neurosci. 12, 1248-1256
Favaro, R., Valotta, M., Ferri, A. L., Latorre, E., Mariani, J., Giachino, C., Lancini, C., Tosetti, V., Ottolenghi, S., Taylor, V. and Nicolis, S. K.
2009). Reelin and Notch1 cooperate in the development of the dentate gyrus. J Neurosci. 29, 8578-8585
Sibbe, M., Forster, E., Basak, O., Taylor, V. and Frotscher, M.
(2010). Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging. Cell Stem Cell 6, 445-456
Lugert, S., Basak, O., Knuckles, P., Haussler, U., Fabel, K., Gotz, M., Haas, C. A., Kempermann, G., Taylor, V. and Giachino, C.
(2010). RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus. J Neurosci. 30, 13794-13807
Ehm, O., Goritz, C., Covic, M., Schaffner, I., Schwarz, T. J., Karaca, E., Kempkes, B., Kremmer, E., Pfrieger, F. W., Espinosa, L., Bigas, A., Giachino, C., Taylor, V., Frisen, J. and Lie, D. C.