Elucidation of the mechanisms determining neural stem cells fate and identification of the niche in the adult SVZ and hippocampus

Antragsteller Professor Verdon Taylor, Ph.D.

Fachliche Zuordnung Entwicklungsneurobiologie

Förderung Förderung von 2006 bis 2010

Projektkennung Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 28996474

Erstellungsjahr 2010

Zusammenfassung der Projektergebnisse

Keine Zusammenfassung vorhanden

(2009). Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh. Nat Neurosci. 12, 1248-1256
Favaro, R., Valotta, M., Ferri, A. L., Latorre, E., Mariani, J., Giachino, C., Lancini, C., Tosetti, V., Ottolenghi, S., Taylor, V. and Nicolis, S. K.
2009). Reelin and Notch1 cooperate in the development of the dentate gyrus. J Neurosci. 29, 8578-8585
Sibbe, M., Forster, E., Basak, O., Taylor, V. and Frotscher, M.
(2010). Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging. Cell Stem Cell 6, 445-456
Lugert, S., Basak, O., Knuckles, P., Haussler, U., Fabel, K., Gotz, M., Haas, C. A., Kempermann, G., Taylor, V. and Giachino, C.
(2010). RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus. J Neurosci. 30, 13794-13807
Ehm, O., Goritz, C., Covic, M., Schaffner, I., Schwarz, T. J., Karaca, E., Kempkes, B., Kremmer, E., Pfrieger, F. W., Espinosa, L., Bigas, A., Giachino, C., Taylor, V., Frisen, J. and Lie, D. C.