Standardization and development of new pain-related models and methods in rodents and humans (human-rodent tandem) (S01)

• Subject Area: Molecular Biology and Physiology of Neurons and Glial Cells ; Clinical Neurology; Neurosurgery and Neuroradiology
• Term: from 2015 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 255156212

Project S01 ensures homogeneity of model systems and measurement techniques to enable reproducibility and meaningful comparison across projects. It also helps with translation and expansion of assessment methods and models to promote studies in both, rodent and pain patients, in unravelling neural circuits of chronic pain. S01 will continue to provide all projects with individually-tailored support with methods and validated preclinical and clinical models. Furthermore, it will expand the spectrum of preclinical models for particularly clinically-relevant pain disorders and develop functional predictive biomarkers in chronic pain patients to improve the efficacy of treatment strategies.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1158: From nociception to chronic pain: Structure-function properties of neural pathways and their reorganisation
• Applicant Institution: Ruprecht-Karls-Universität Heidelberg
• Project Heads: Dr. Anke Tappe-Theodor; Professor Dr. Rolf-Detlef Treede