Project Details
Projekt
GRK 757: Roles of Eicosanoids in Biology and Medicine
Subject Area
Basic Research in Biology and Medicine
Term
from 2002 to 2010
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 273393
The research training group "Roles of Eicosanoids in Biology and Medicine" aims to develop a joint academic and research venture between the Johann Wolfgang Goethe University in Frankfurt and the Department of Medical Chemistry at the Karolinska Institute in Stockholm. The academic goal of the program is to enable qualified graduate students/PhD students and postdoctoral fellows interested in following a career in molecular medicine, pharmacy and biology to extend their understanding of the physiological and pathophysiological roles of eicosanoids in a multidisciplinary scientific environment with access to a wide spectrum of established methods. Scientific aims of the program are to investigate the molecular mechanisms of action of eicosanoids using complementary approaches (chemical, biochemical, molecular, pharmacological, physiological and clinical) designed by both institutions involved in this program.
Eicosanoids are lipid autacids which play a key role in a number of physiological and pathophysiological events, during inflammatory reactions, neoplastic transformation and proliferation. The present research and education program extends the realms and intensity of the collaboration which has existed to-date and is intended to make optimal use of the different but complementary experimental approaches and areas of expertise of the two institutions for the education of graduate students. Whereas the Karolinska Institute will preferentially focus on the molecular biology of eicosanoids and arachidonic acid pathways, the pharmacology of eicosanoids and questions related to their clinical relevance will be investigated in Frankfurt.
Eicosanoids are lipid autacids which play a key role in a number of physiological and pathophysiological events, during inflammatory reactions, neoplastic transformation and proliferation. The present research and education program extends the realms and intensity of the collaboration which has existed to-date and is intended to make optimal use of the different but complementary experimental approaches and areas of expertise of the two institutions for the education of graduate students. Whereas the Karolinska Institute will preferentially focus on the molecular biology of eicosanoids and arachidonic acid pathways, the pharmacology of eicosanoids and questions related to their clinical relevance will be investigated in Frankfurt.
DFG Programme
International Research Training Groups
International Connection
Sweden
Applicant Institution
Goethe-Universität Frankfurt am Main
IRTG-Partner Institution
Karolinska Institutet
Spokesperson
Professor Dr. Dieter Steinhilber
Participating Researchers
Privatdozent Dr. Joachim Bargon; Professor Dr. Bernhard Brüne; Professor Dr. Rudi Busse (†); Professorin Ingrid Fleming, Ph.D.; Professor Dr. Gerd Geißlinger; Professorin Dr. Sabine Grösch; Professorin Dr. Andrea Huwiler (†); Professor Dr. Jörn Lötsch; Professor Dr. Josef M. Pfeilschifter; Dr. Oliver Schröder; Professor Dr. Jürgen Stein
IRTG-Partner: Spokesperson
Professor Dr. Jesper Z. Haeggström
