New cyclic peptoids - design and syntheses

• Applicant: Professor Dr. Stefan Bräse
• Subject Area: Organic Molecular Chemistry - Synthesis and Characterisation
• Term: from 2014 to 2018
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 260963601

For over 30 years, peptoids are a well-known class of compounds. Since then, they are constantly developed. Due to their fast and easy synthesis, peptoids represent popular mimetics that can be used in many ways. Through the correlation of efficacy and structure the basic research focusses on the development of individual structural motifs that mimic known peptide structures. On the basis of successful preliminary work, the aim of this project is to develop novel tertiary structures of peptoid scaffolds, which later serve for the complexation of metals. Furthermore, we intend to advance ligand systems that specifically bind metals and allow simple and simultaneous incorporation into this newly generated scaffolds.

• DFG Programme: Research Grants