Project Details
Analysis of P5B ATPase Function
Applicant
Privatdozent Dr. Eric Lambie
Subject Area
Developmental Biology
Cell Biology
Cell Biology
Term
from 2014 to 2020
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 257149307
Final Report Year
2021
Final Report Abstract
No abstract available
Publications
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Novel Alleles of gon-2, a C. elegans Ortholog of Mammalian TRPM6 and TRPM7, Obtained by Genetic Reversion Screens. PLoS One. 2015 Nov 25;10(11):e0143445
Lambie EJ, Bruce RD 3rd, Zielich J, Yuen SN
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Establishment of a CRISPR/Cas9-based strategy for inducible protein dimerization. MicroPubl Biol. 2018 Apr 17. Erratum in: MicroPubl Biol. 2019 Dec 02
Zielich J, Mangal S, Zanin E, Lambie E
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Overlapping expression patterns and functions of three paralogous P5B ATPases in Caenorhabditis elegans. PLoS One. 2018 Mar 16;13(3):e0194451
Zielich J, Tzima E, Schröder EA, Jemel F, Conradt B, Lambie EJ
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Rapamycin-induced proteindimerization as a tool for C. elegans research. MicroPubl Biol. 2018 Mar20. Erratum in: MicroPubl Biol. 2019 Dec 02
Mangal S, Zielich J, Lambie E, Zanin E
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ATP13A2 deficiency disrupts lysosomal polyamine export. Nature. 2020 Feb;578(7795):419-424
van Veen S, Martin S, Van den Haute C, Benoy V, Lyons J, Vanhoutte R, Kahler JP, Decuypere JP, Gelders G, Lambie E, Zielich J, Swinnen JV, Annaert W, Agostinis P, Ghesquière B, Verhelst S, Baekelandt V, Eggermont J, Vangheluwe P
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ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31198-31207
Vrijsen S, Besora-Casals L, van Veen S, Zielich J, Van den Haute C, Hamouda NN, Fischer C, Ghesquière B, Tournev I, Agostinis P, Baekelandt V, Eggermont J, Lambie E, Martin S, Vangheluwe P