SPP 1857:  Elektromagnetische Sensoren für Life Sciences (ESSENCE)

• Subject Area: Computer Science, Systems and Electrical Engineering ; Biology ; Chemistry ; Materials Science and Engineering ; Medicine
• Term: from 2015 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 255715243

The central idea of the Priority Program ESSENCE is to establish interdisciplinary research in the field of electromagnetic sensors, whose principle of sensing or measurement is based on the interaction between the electromagnetic fields of the sensor and the matter to be detected or analyzed with a special focus in life sciences. The matter of interest could be biomolecules, cells, tissues and organs or other parts of the body of animals or humans in biology and medicine as well as materials, chemical substances and mixtures of it in pharmacology, food chemistry, agricultural engineering, environmental analysis and monitoring. Therefore, senor elements at micro-, millimeter- and THz waves are very promising because of their high-performance potential, combining a high sensitivity, good penetration and spatial resolution as well as marker- and reactionless operation.

• DFG Programme: Priority Programmes
• International Connection: France

Projects

• A silicon-based terahertz near-field imaging array for ex vivo life-science applications - Phase 2 (Applicants MacGrogan, Gaetan ;  Pfeiffer, Ullrich ;  Zimmer, Thomas )
• APTERA II - Electromagnetic THz- and mm-wave Sensors for African Trypanosomes using RNA Aptamer-Derivatized Surface Layers (Applicants Damm, Christian ;  Göringer, H. Ulrich )
• BURNTwo - Burn Wound Assessment Using Microwave Imaging Radar Based Near Field Techniques - Phase II (Applicants Goertz, Ole ;  Vossiek, Martin )
• Coordination Funds (Applicant Jakoby, Rolf )
• Dual-mode microwave applicator for diagnosis and thermal ablation treatment of organic tissue (Applicants Jakoby, Rolf ;  Vogl, Thomas J. )
• Elucidating stress responses in bacterial biofilms using electromagnetic sensors and transcriptome analysis on single-cell level (Applicants Jakoby, Rolf ;  Rapp, Bastian Ernst ;  Schwartz, Thomas )
• Integrated Lab-on-Chip Terahertz-Spectroscopy Platform in BiCMOS Technology II (THz-LoC II) (Applicants Kissinger, Dietmar ;  Tillack, Bernd )
• Integrated microstructures for label-free interrogation of protein conformational dynamics by plasmon-enhanced THz spectroscopy (Applicants Capellini, Ph.D., Giovanni ;  Piehler, Jacob ;  Witzigmann, Bernd )
• Lab-in-a-tube: non-linear dielectric spectroscopy for multiparametric bioanalysis (Applicants Karnaushenko, Daniil ;  Medina Sánchez, Mariana )
• Multi-band millimeter wave / terahertz breath sensor based on molecular absorption spectroscopy (Applicants Hübers, Heinz-Wilhelm ;  Koczulla, Andreas Rembert ;  Schmalz, Klaus )
• Single-chip in-cell ESR and online reaction monitoring using VCO-based detectors (Applicants Anders, Jens ;  Bittl, Robert ;  Korvink, Jan Gerrit )
• Ultra-broadband dielectric spectroscopy of biomolecules (Applicant Hölzel, Ralph )
• Ultra-Fast Bio-Molecule Detection based on Radio-Frequency Nano-Pore and Nano-Channel Circuits (Applicant Blick, Robert H. )
• Ultrasensitive marker-free biomolecular THz-detection for tumor related analytics: PCR-free sensitivity, biomolecular extension and biological relevance (Applicants Bosserhoff, Anja-Katrin ;  Haring Bolívar, Peter ;  Wigger, Anna Katharina )

• Spokesperson: Professor Dr.-Ing. Rolf Jakoby