Holistic approach to the bacterial genetic regulation system

• Applicant: Professor Dr. Georgi Muskhelishvili
• Subject Area: General Genetics and Functional Genome Biology
• Term: from 2013 to 2017
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 243154253

• Final Report Year: 2019

Final Report Abstract

No abstract available

Publications

• (2013) DNA thermodynamic stability and supercoil dynamics determine the gene expression program during the bacterial growth cycle. Mol BioSyst 9, 1643-1651
  Sobetzko P, Glinkowska M, Travers A & Muskhelishvili G
  (See online at https://doi.org/10.1039/C3MB25515H)
• (2015) Chromosomal "stress-response" domains govern the spatiotemporal expression of the bacterial virulence program. MBio 6 (3) e00353-15
  Jiang X, Sobetzko P, Nasser W, Reverchon S and Muskhelishvili G
  (See online at https://doi.org/10.1128/mBio.00353-15)
• (2015) Chromosomal position shift of a regulatory gene alters the bacterial phenotype. Nucl Acids Res 43, 8215- 8226
  Gerganova V, Berger M, Zaldastanishvili E, Sobetzko P, Lafon C, Mourez M, Travers A and Muskhelishvili G
  (See online at https://doi.org/10.1093/nar/gkv709)
• (2015) Upstream binding of idling RNA polymerase modulates transcription initiation from a nearby promoter. J Biol Chem 290: 8095-109
  Gerganova V, Maurer S, Stoliar L, Japaridze A, Nasser W, Kutateladze T, Travers A and Muskhelishvili G
  (See online at https://doi.org/10.1074/jbc.M114.628131)
• (2016) Global transcriptional response of Dickeya dadantii to environmental stimuli relevant to the plant infection. Environ Microbiol 18(11), 3651-3672
  Jiang X, Zghidi-Abouzid O, Oger-Desfeux C, Hommais F, Greliche N, Muskhelishvili G, Nasser W, Reverchon S
  (See online at https://doi.org/10.1111/1462-2920.13267)
• (2016) Temporal control of Dickeya dadantii main virulence gene expression by growth phase-dependent alteration of regulatory nucleoprotein complexes. Biochim Biophys Acta 1859(11), 1470-1480
  Duprey A, Muskhelishvili G, Reverchon S, Nasser W
  (See online at https://doi.org/10.1016/j.bbagrm.2016.08.001)
• (2016) Virulence Program of a Bacterial Plant Pathogen: The Dickeya Model. Prog Mol Biol Transl Sci. 2016; 142:511-92
  Reverchon S, Muskhelisvili G, Nasser W
  (See online at https://doi.org/10.1016/bs.pmbts.2016.05.005)
• (2017) Spatial organization of DNA sequences directs the assembly of bacterial chromatin by a nucleoid-associated protein. J Biol Chem 292(18):7607-7618
  Japaridze A, Renevey S, Sobetzko P, Stoliar L, Nasser W, Dietler G and Muskhelishvili G
  (See online at https://doi.org/10.1074/jbc.M117.780239)