Epstein-Barr virus DNA acquires cellular chromatin early in infection (A13)

• Subject Area: General Genetics and Functional Genome Biology
• Term: from 2013 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 213249687

We shall study the epigenetic and molecular events in the pre-latent phase of viral infection, when Epstein-Barr virus reprograms the resting B-lymphocytes into activated and proliferating B blasts. The project aims at characterising the nature and principles of chromatin acquisition of epigenetically naïve, histone and nucleosome-free DNA in a tractable, highly reproducible mammalian cell model.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1064: Chromatin Dynamics
• Applicant Institution: Ludwig-Maximilians-Universität München
• Project Head: Professor Dr. Wolfgang Hammerschmidt