Control of membrane trafficking by Rab GTPases activating proteins

Applicant Professor Dr. Francis Barr

Subject Area Cell Biology

Term from 2006 to 2009

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 23633737

Final Report Year 2014

Final Report Abstract

No abstract available

Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells. J Cell Sci. 2007 Sep 1;120(Pt 17):2997-3010
Haas AK, Yoshimura S, Stephens DJ, Preisinger C, Fuchs E, Barr FA
Functional dissection of Rab GTPases involved in primary cilium formation. J Cell Biol. 2007 Jul 30;178(3):363-9
Yoshimura S, Egerer J, Fuchs E, Haas AK, Barr FA
Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways. J Cell Biol. 2007 Jun 18;177(6):1133-43
Fuchs E, Haas AK, Spooner RA, Yoshimura S, Lord JM, Barr FA
Analysis of Rab GTPase and GTPase-activating protein function at primary cilia. Methods Enzymol. 2008;439:353-64
Yoshimura S, Haas AK, Barr FA
Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors. J Cell Biol. 2010 Oct 18;191(2):367-81.
Yoshimura S, Gerondopoulos A, Linford A, Rigden DJ, Barr FA
Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C. J Cell Biol. 2010 Apr 19;189(2):223-32
Hsu C, Morohashi Y, Yoshimura S, Manrique-Hoyos N, Jung S, Lauterbach MA, Bakhti M, Grønborg M, Möbius W, Rhee J, Barr FA, Simons M