Development and characterization of engineered riboswitches (A02)

• Subject Area: Biochemistry
• Term: from 2011 to 2023
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 161793742

Synthetic riboswitches emerge as an important tool in Chemical and Synthetic Biology but their development is still challenging. We succeeded in establishing methods for the rapid and successful identification of new riboswitches with improved regulatory properties to not only further expand riboswitch applicability, but also to fully exploit their potential as control elements in regulating gene expression.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 902: Molecular Principles of RNA-based Regulation
• Applicant Institution: Goethe-Universität Frankfurt am Main
• Co-Applicant Institution: Technische Universität Darmstadt
• Project Head: Professorin Dr. Beatrix Süß