Project Details
Etablierung eines humanen ex-vivo Zellkultur-Modells aus "reprogrammierten" Fibroblasten (iPS-Zellen) von Parkinson-Patienten mit LRRK2-Muation
Applicant
Dr. Martina Wölfle
Subject Area
Molecular and Cellular Neurology and Neuropathology
Term
from 2010 to 2013
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 176910480
Final Report Year
2014
Final Report Abstract
No abstract available
Publications
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Genetic Correction of a LRRK2-Mutation in Human iPSCs Links Parkinsonian Neurodgeneration to ERK-Dependent Changes in Gene Expression. Cell Stem Cell. 2013 Mar 7;12(3):354-67
Reinhardt P, Schmid B, Burbulla LF, Schöndorf DC, Wagner L, Glatza M, Höing S, Hargus G, Heck SA, Dhingra A, Wu G, Müller S, Brockmann K, Kluba T, Maisel M*, Krüger R, Berg D, Tsytsyura Y, Thiel CS, Psathaki OE, Klingauf J, Kuhlmann T, Klewin M, Müller H, Gasser T, Schöler HR, Sterneckert J