Metabolic interaction between Dinoroseobacter shibae and Thallasiosira rotula (C03)

• Subject Area: Metabolism, Biochemistry and Genetics of Microorganisms
• Term: from 2010 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 34509606

The principle goal is the understanding of the metabolic interaction between D. shibae and the diatom Thalassiosira rotula. For this, a detailed analysis of the T. rotula metabolism under different environmental conditions is planned. Furthermore, we propose to apply stable-isotope assisted metabolomics and metabolic flux analysis to shed light on how a close interaction of these two organisms impacts cellular metabolism and homeostasis of each partner. We will address this question with a combined experimental and modelling approach based on the genome sequences of T. rotula and D. shibae.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 51: Ecology, Physiology and Molecular Biology of the Roseobacter Clade: Towards a Systems Biology Understanding of a Globally Important Clade of Marine Bacteria
• Applicant Institution: Carl von Ossietzky Universität Oldenburg
• Project Heads: Professor Dr. Karsten Hiller, since 1/2018; Dr. Kerstin Schmidt-Hohagen; Professor Dr. Dietmar Schomburg, until 12/2017