Function and ecological significance of secondary metabolites produces by Roseobacter spp. for interactive relationships (B02)

• Subject Area: Microbial Ecology and Applied Microbiology ; Biological and Biomimetic Chemistry
• Term: from 2010 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 34509606

During the third application phase this project will investigate the significance of secondary metabolites produced by Phaeobacter inhibens for its interaction with the diatom Thalassiosira rotula. Analysis of the T. rotula genome by the TRR51 consortium and subsequently comprehensive studies on the interaction of P. inhibens and the diatom will be performed. Mutants negative for production of tropodithietic acid or quorum sensing will be compared to the wild type for their competition capabilities during bacterial colonization of the diatom. Furthermore, different physiological states of the diatom will be considered, concerning the influence on mutualism or parasitism by the bacteria.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 51: Ecology, Physiology and Molecular Biology of the Roseobacter Clade: Towards a Systems Biology Understanding of a Globally Important Clade of Marine Bacteria
• Applicant Institution: Carl von Ossietzky Universität Oldenburg
• Project Heads: Professor Dr. Thorsten Brinkhoff; Professor Dr. Meinhard Simon, until 12/2013