Mesoscopic 2D- and 3D-scaffolds made of spider silk proteins providing bacteriostatic surfaces and anti-bacterial properties (A08)

• Subject Area: Biomaterials
• Term: from 2009 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 79971943

In this project influences of molecular and varying processing parameters on distinct properties of recombinant spider silk materials have been investigated. The results reveal insights into molecular details of silk assembly. Based on the new findings it has been able to assemble biotech spider silk-like fibers with nature-like mechanical properties. Further, it has been possible to coat implants and catheters to improve their biocompatibility and to reduce unwanted side-effects upon implantation. Finally, self-supporting spider silk films were compounded with nanoclay to yield gas and water vapor barriers.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 840: From Particulate Nanosystems to Mesotechnology
• Applicant Institution: Universität Bayreuth
• Project Head: Professor Dr. Thomas Scheibel