Project Details
Identification of early imaging biomarkers of efficacy for anti-angiogenic therapy in neuroendocrine tumors (B08 (A04))
Subject Area
Nuclear Medicine, Radiotherapy, Radiobiology
Term
from 2009 to 2021
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 68647618
Treatment of aggressive neuroendocrine tumors remains a clinical challenge as effective options are limited. Using a representative model of endogenous neuroendocrine tumors we plan to evaluate novel therapeutic approaches and identify imaging biomarkers for early assessment of drug efficacy. We will also establish xenograft models from patients-derived tumors to test anti-angiogenic therapy. If translated into clinical settings, our results may help improve and individualize the treatment of aggressive neuroendocrine tumors.
DFG Programme
Collaborative Research Centres
Applicant Institution
Technische Universität München (TUM)
Project Head
Dr. Natalia S. Pellegata