Project Details

Professor Oliver T. Fackler, Ph.D.

Address Universitätsklinikum Heidelberg
Zentrum für Infektiologie
Sektion Integrative Virologie
Im Neuenheimer Feld 344
69120 Heidelberg

Projects

As Applicant
- Current projects
  - Characterization of HIV infection in resting CD4 T-cells (Research Grants)
  - Mechanisms of actin polymerization in T lymphocyte nuclei (Research Grants)
  - Role of lncRNAs in cell activation, actin remodeling and HIV latency in CD4 T lymphocytes (Research Grants)
  - Molecular mechanisms of CD4 T-B cell communication and its disruption by HIV-1 (Research Grants)
- Completed projects
  - Analyse der molekularen Mechanismen des Pathogenitätsfaktors Nef des Humanen Immundefizienzvirus Typ 1 (HIV-1) (Independent Junior Research Groups)
  - Design und Charakterisierung eines Moleküls zur Inhibierung des HIV Pathogenesefaktors Nef (Research Grants)
  - Rho GTPases and Diaphanous related Formins in HIV-1 replication (Priority Programmes)
  - Regulationsmechanismen und physiologische Funktion des Diaphanous Formins FHOD1 (Research Grants)
  - Mechanisms of cell motility inhibition by the HIV-1 pathogenesis factor NEF (Research Grants)
  - Role of the Diaphanous Formin FHOD1 and its interaction with nesprin-2-giant in nuclear migration (Research Grants)
  - Characterization of the antiviral immunity factor CD317/tetherin (Research Grants)
  - Antagonism of Host Cell Restriction and Sensing by HIV-1 Nef (Priority Programmes)
  - Coordination Funds (Priority Programmes)
  - The role of TREX1 for innate sensing human endogenous retroviruses (Priority Programmes)
As Spokesperson
- Completed projects
  - GRK 1188: Quantitative Analysis of Dynamic Processes in Membrane Transport and Translocation (Research Training Groups)
  - SPP 1923: Innate Sensing and Restriction of Retroviruses (Priority Programmes)
As Project Head
- Current projects
  - HIV-1 spread in complex cell systems (Collaborative Research Centres)
- Completed projects
  - Nef and Lipid Rafts: Functional Coordination of the HIV Pathogeneticity factor during particle release and TCR Signaling (CRC/Transregios)
  - Modulation of architecture and function of the immunological synapse by the HIV pathogenesis factor Nef (Collaborative Research Centres)
  - Membrane microdomain interactions of the HIV-1 pathogenicity factor Nef (CRC/Transregios)
As Co-Investigator
- Completed projects
  - Mechanisms of inflammasome activation and pyroptosis induction by HIV (Priority Programmes)

Servicenavigation

Hauptnavigation

Professor Oliver T. Fackler, Ph.D.

Additional Information

Servicenavigation

Hauptnavigation

Professor Oliver T. Fackler, Ph.D.

Additional Information

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