Project Details

Professor Dr. Oliver Seitz

Address Humboldt-Universität zu Berlin
Mathematisch-Naturwissenschaftliche Fakultät
Institut für Chemie
Brook-Taylor-Straße 2
12489 Berlin

Projects

As Applicant
- Current projects
  - Self-cleaving Molecular Beacons for amplified nucleic acid detection (Research Grants)
  - Bispecific DNA-Peptide Probes for Targeting and Modulating Oncogenic Receptor Pairs (Research Grants)
  - Catalytically active high performance auxiliaries for the proximity-induced native chemical peptide ligation (Research Grants)
- Completed projects
  - Steuerung und Katalyse der chemischen Verknüpfung von PNA-Konjugaten durch Oligonucleotid-Template (Research Grants)
  - Der Austausch von Nucleobasen durch Fluorophorsysteme. Parallele Synthese und biophysikalische Untersuchung intern fluoreszenzmarkierter Peptidnucleinsäuren (Research Grants)
  - DNA-Templat-kontrollierte Verknüpfung von PNA-Aminosäurekonjugaten (Heisenberg Fellowships)
  - Duplex-Oligodesoxynucleotide mit C-glycosidisch gebundenen Basensurrogaten zur Untersuchung des Basen-Ausklapp-Mechanismus und selektiven Inhibition von DNA-Methyltransferasen (Research Grants)
  - DNA-katalysierte Verknüpfungs-Cyclisierungs-Reaktionen: Entwicklung einer hochselektiven, signalamplifizierenden Methode für die Mutationsanalyse (Research Grants)
  - Selbstreinigende Synthese von Peptidthioestern zum Aufbau von Proteindomänen auf Arrays und auf Beads (Research Grants)
  - Eine allgemeine Methode zur Fmoc-basierten Festphasensynthese von Peptidthioestern über S>S-Acyltransfer (Research Grants)
  - Basenlabile Auxiliare für die cysteinfreie Peptidverknüpfung (Research Grants)
  - RNA-controlled synthesis of peptides via peptidyl transfer reactions with peptide-nucleic acid conugates (Research Grants)
  - Energy transfer and enforced intercalation: Responsive as well as bright DNA-based high performance probes for RNA imaging in live cells (Research Grants)
  - Cellular imaging of RNA C-to-U editing (Priority Programmes)
  - Peptide-templated bioconjugation of proteins on and in live cells for studies of GPCR trafficking and crosstalk (Priority Programmes)
  - High performance auxiliaries for a cysteine-tolerant native chemical ligation at arbitrary sites (Research Grants)
  - Brightness- and contrast-enhanced RNA hybridization probes for mRNA imaging and recognition of living cells (Research Grants)
As Participating Researcher
- Current projects
  - GRK 2473: Bioactive Peptides – Innovative Aspects of Synthesis and Biosynthesis (Research Training Groups)
- Completed projects
  - GSC 1013: Graduate School of Analytical Sciences Adlershof (SALSA) (Graduate Schools)
As Project Head
- Current projects
  - Development and application of nanoviscosity probes in advanced FLIM studies on synthetic and native hydrogels in vitro (Collaborative Research Centres)
  - Semi-synthetic approaches to probe mucin function (Collaborative Research Centres)
- Completed projects
  - Nucleic acid-ligand conjugates - Precision tools for high affinitry and high specificity interactions in Chemistry and Biology (Collaborative Research Centres)

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Professor Dr. Oliver Seitz

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Oliver Seitz

Additional Information

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