Project Details

Professor Dr. Roland Schüle

Address Albert-Ludwigs-Universität Freiburg
Klinik für Urologie
Arbeitsgruppe Hormone Dependent Cancer
Breisacher Straße 66
79106 Freiburg

Projects

As Applicant
- Current projects
  - The role of the histone demethylase LSD1 in the pathogenesis of AML (Research Units)
  - Urologial Diseases in a Aging Society: From Genetic to Medical Csre (UroAgeCare) (Workshops for Early Career Investigators)
  - P5: Dissection of KMT9 biology in urothelial carcinoma (Research Units)
- Completed projects
  - Modulation circadianer Regulationsmechanismen durch den nukleären Orphan Rezeptor RZRbeta (Priority Programmes)
  - Funktionelle Charakterisierung des nukleären Orphan Rezeptors RORß (Research Grants)
  - Funktionelle Charakterisierung der Transkriptionsfaktoren SEF-2 und MIBP1 (Research Grants)
  - FHL2 modulierte Osteoblastenaktivität: Ein neuer Weg zur Inhibition von Osteoporose (Research Grants)
  - Charakterisierung der Histondemethylase LSD1 (Research Grants)
  - FHL2 modulierte Osteoblastenaktivität: Ein neuer Weg zur Inhibition von Osteoporose (Research Grants)
  - Target basierte Entwicklung neuer Hemmstoffe der Lysin-Dementhylase LSDI und deren Einfluss auf die Regulation des Androgenrezeptors (Research Grants)
  - Control of histone demethylase activity: An innovative therapeutic concept to fight hormone refractory prostate cancer (Reinhart Koselleck Projects)
  - Die Regulation des Tumorsuppressors p53 durch den neuen INHAT-Repressor NIR (Research Grants)
  - The novel lysine methyltransferase ILSE1 controls castration-resistant prostate cancer (Research Grants)
As Spokesperson
- Completed projects
  - SFB 992: Medical Epigenetics (MEDEP) - From Basic Mechanisms to Clinical Applications (Collaborative Research Centres)
As Participating Researcher
- Current projects
  - EXC 2189: CIBSS - Centre for Integrative Biological Signalling Studies (Clusters of Excellence (ExStra))
- Completed projects
  - EXC 294: Centre for Biological Signalling Studies (bioss) - From Analysis to Synthesis (Clusters of Excellence)
As Project Head
- Current projects
  - Central Tasks of the Collaborative Research Centre (Collaborative Research Centres)
- Completed projects
  - Funktionelle Charakterisierung des Androgenrezeptor Koaktivatorproteins FHL2 (Collaborative Research Centres)
  - Strategien zur gezielten Modulation der transkriptionellen Aktivität des Tumorsuppressorproteins WT1 (Collaborative Research Centres)
  - Control of adipogenesis by the signal-regulated INHAT-repressor NIR (Collaborative Research Centres)
  - Assembly and signal-mediated regulation of the androgen receptor/LSD1 histone demethylation complex (Collaborative Research Centres)
  - The novel arginine methyltransferase PRMT10 controls tumor growth and metastatic disease (Collaborative Research Centres)
  - The KMT9 protein machinery is a novel chromatin writer (Collaborative Research Centres)
  - Characterisation of the lysine methyltransferases KMT9 and KMT10 (Collaborative Research Centres)
As Co-Investigator
- Current projects
  - Understanding the relevance of RAI2 activity in emerging therapy-resistance of castration-resistant prostate cancer (Research Grants)

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Professor Dr. Roland Schüle

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Roland Schüle

Additional Information

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