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Institution
Universität Leipzig
Paul-Flechsig-Institut für Hirnforschung
Address
Liebigstraße 19
04103 Leipzig
Deutschland
GERiT
This institution in GERiT
04103 Leipzig
Projects
Research Grants
Current projects
Pyroglutamate modification of a-synuclein in human synucleinopathies
(Applicant
Roßner, Steffen
)
The role of brevican in cochlear function and normal hearing through its interaction with hair cells and bone
(Applicant
Sonntag, Mandy
)
Unraveling the metabolic action of polyamines on muscle homeostasis in health & obesity
(Applicant
Ost, Mario
)
Completed projects
Are alpha-synuclein fragments novel substrates of glutaminyl cyclase?
(Applicant
Roßner, Steffen
)
Die Bedeutung von Gliotransmittern für den Verlauf einer reaktiven Gliose
(Applicant
Pannicke, Thomas
)
Drug-Targeting mit Nanopartikeln gegen experimentell induzierte ß-Amyloid-Ablagerungen und abnorm phosphoryliertes Protein Tau im Gehirn von Kaninchen und transgenen Mäusen mit humanem ß-Amyloid-Präkursorprotein
(Applicant
Härtig, Wolfgang
)
Effekt der exzitatorischen synaptischen Aktivität auf die Prozessierung des Amyloidvorläuferproteins APP
(Applicant
Roßner, Steffen
)
Enzymatic regulation of CCL2 bioactivity in neuroinflammation
(Applicants
Roßner, Steffen
;
Schilling, Stephan
)
Identifikation und funktionelle Charakterisierung molekularer Mediatoren der Kaliumkanalexpression in retinalen Gliazellen
(Applicant
Biedermann, Bernd
)
Interaction of interleukin-1 with the cholinergic signal transduction cascade and its importance for cholinergic deficits in Alzheimer´s disease
(Applicant
Schliebs, Reinhard
)
Is the neurotoxicity of amyloid-beta AGE-related?
(Applicant
Schliebs, Reinhard
)
Morphogenetische Bedeutung von p21ras in differenzierten Neuronen: Morphologische Analyse, Modellierung und Computersimulation
(Applicant
Gärtner, Ulrich
)
Pathomorphologie und Pathophysiologie der Borna-Disease-Virus (BDV)-induzierten Netzhautdegeneration
(Applicant
Pannicke, Thomas
)
Regulation des Amyloidvorläuferprotein-Metabolismus und der ß-Amyloidplaque-Bildung durch Proteinkinase C-abhängige Mechanismen in vivo
(Applicant
Roßner, Steffen
)
Selektive Proteinkinase-Inhibitoren als Wirkstoffe gegen Neurodegeneration
(Applicants
Hilgeroth, Andreas
;
Holzer, Max
;
Sippl, Wolfgang
)
Signatures of modified Abeta peptides in brains of Alzheimer’s disease subjects revealed by novel monoclonal antibodies
(Applicants
Roßner, Steffen
;
Schilling, Stephan
)
Site specific phosphorylation of tau protein employs signal transduction causing neurodegeneration
(Applicant
Holzer, Max
)
Research Units
Completed projects
CD14 as a Gate Keeper in Microglial Responses to PAMPs and DAMPs
(Applicant
Brück, Wolfgang
)
Regulation of Wnt signaling in macrophage-induced malignant invasion
(Applicant
Binder, Claudia
)
Collaborative Research Centres
Completed projects
Thrombin als Stimulus und Modulator mikroglialer Aktivierung
(Project Head
Hanisch, Uwe-Karsten
)
CRC/Transregios
Completed projects
Integrated Research Training Group
(Project Heads
Hanisch, Uwe-Karsten
;
Kettenmann, Helmut
)
Phenotypic diversity of microglia
(Project Heads
Brück, Wolfgang
;
Hanisch, Uwe-Karsten
)
Additional Information
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